Auto57%Harbor: pendingAgentic / Tool UseMultimodalKnowledge & Reasoning

CASE longitudinal multimodal benchmark

CASE: Clinical Agents for Seeking Evidence Longitudinal Multimodal Benchmark

A longitudinal medical reasoning benchmark built on UK Biobank data comprising over 50k questions and multi-sequence MRI records from ~4.7k participants, requiring agents to autonomously gather evidence across visits.

How to run

ltb · case-longitudinal-multimodal-benchmark
$ npm i -g lettokenburn-cli
$ ltb bench info case-longitudinal-multimodal-benchmark

External harness. No Harbor adapter has been generated for this benchmark yet. `ltb bench info` prints the known links.

Runs happen on your machine with your own subscription; only the score summary is pushed. CLI docs

Scores

13 sourced entries
HarnessSourceConfidenceLink
CASE75.1N/AIndependentmediumSep 30, 2026arxiv.org
Kimi K369.5N/AIndependentmediumSep 30, 2026arxiv.org
Qwen3.7 Plus67.7N/AIndependentmediumSep 30, 2026arxiv.org
Claude Opus 4.865.8N/AIndependentmediumSep 30, 2026arxiv.org
GPT-5.4-030565.7N/AIndependentmediumSep 30, 2026arxiv.org
Qwen3.8 Max58.3N/AIndependentmediumSep 30, 2026arxiv.org
Gemini-3.5-flash56.3N/AIndependentmediumSep 30, 2026arxiv.org
Lingshu-32B50.3N/AIndependentmediumSep 30, 2026arxiv.org
Qwen3-VL-8B-Instruct47.1N/AIndependentmediumSep 30, 2026arxiv.org
Lingshu-7B46.7N/AIndependentmediumSep 30, 2026arxiv.org
Kimi K2.642.0N/AIndependentmediumSep 30, 2026arxiv.org
MedGemma-1.5-4B41.4N/AIndependentmediumSep 30, 2026arxiv.org
MedGemma-27B27.5N/AIndependentmediumSep 30, 2026arxiv.org

Every number links to where it was published. Low-confidence rows are muted and need per-cell verification.

Reproduced by the community

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About

Content & Construction: The CASE benchmark consists of a patient-level tool-use harness where each question links to an environment containing clinical context (ICD-10 diagnoses) and heterogeneous multi-sequence MRIs from baseline and follow-up visits. Agents must autonomously select which organs, modalities, slices, and specialist tools to inspect before answering multiple-choice questions.

Scoring & Findings: Accuracy reflects the agent's ability to choose relevant evidence rather than just reasoning over fixed context. The benchmark supports agentic reinforcement learning; experiments show a Qwen3-VL-8B based agent achieves significant relative improvements in answer accuracy compared to frontier models like GPT-5.4 and Claude Opus 4.8.